5c8e_EG : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS CARH BOUND TO ADENOSYLCOBALAMIN AND A 26-BP DNA SEGMENT
reference	Drennan et al. Nature 526 536 2015
source	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) / Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) / Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) / Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
experiment	X-ray (resolution=3.89, R-factor=?)
structural superfamily	Putative DNA-binding domain;Cobalamin vitamin B12-binding domain;
reference complex	5c8e_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5c8e_E interface=19,20,37, vytiaeveamtglsaevlRQwerrygfpkprrtpggHrlysaedvealktikrwleegatpkaairrylaqevrpedlgtglleallrgdlagaealfrrglrfwgpegvlehlllpvlrevgeawhrgeigvaeehlastflrarlqelldlagfppgppvlvttppgerheigamlaayhlrrkgvpalylgpdtplpdlralarrlgagavvlsavlseplralpdgalkdlaprvflggqgagpeearrlgaeymedlkglaealwlpr > 5c8e_G interface=25,26,29,30,43, hmtssgvytiaeveamtglsaevlRQweRRygfpkprrtpggHrlysaedvealktikrwleegatpkaairrylaqevrpedlgtglleallrgdlagaealfrrglrfwgpegvlehlllpvlrevgeawhrgeigvaeehlastflrarlqelldlagfppgppvlvttppgerheigamlaayhlrrkgvpalylgpdtplpdlralarrlgagavvlsavlseplralpdgalkdlaprvflggqgagpeearrlgaeymedlkglaealwlprg
interface signature	RQH/RQRRH

Estimated binding specificities ?

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# IC=1.156 IC/col=0.128 n_of_columns=9

specificity:

A |  38  24  24  24  25  24   9  12  10
C |  19  24  24  24  22  24  11  12  10
G |  19  24  24  24  22  24   9  60  13
T |  20  24  24  24  27  24  67  12  63

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updated Tue Sep 10 02:54:48 2024