5cbx_EF : 3D-footprint complex

structure name	ANCGR DNA BINDING DOMAIN - (+)GRE COMPLEX
reference	Ortlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
source	UNCLASSIFIED
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cbx_E interface=26,27,31, ppkiclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrfrkclqagmnle > 5cbx_F interface=26,27,31, ppkiclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrfrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.333 IC/col=0.564 n_of_columns=13

specificity:

A |  12  24  66   0  96  24  24  24   0   0   6  24   7
C |   8  24  12  96   0  24  24  24   0   0  19  24  83
G |  12  24   6   0   0  24  24  24   0  96  12  24   0
T |  64  24  12   0   0  24  24  24  96   0  59  24   6

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updated Mon Jan 5 15:10:10 2026