5cbx_EF : 3D-footprint complex

structure name	ANCGR DNA BINDING DOMAIN - (+)GRE COMPLEX
reference	Ortlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
source	UNCLASSIFIED
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbx_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cbx_E interface=26,27,31, ppkiclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrfrkclqagmnle > 5cbx_F interface=26,27,31, ppkiclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrfrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.071 IC/col=0.544 n_of_columns=13

specificity:

A |   6  24  60   0  96  24  24  24   0   0  12  24   6
C |  12  24   6  96   0  24  24  24   0   0  24  24  84
G |  18  24  12   0   0  24  24  24   0  96  12  24   0
T |  60  24  18   0   0  24  24  24  96   0  48  24   6

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updated Wed Jul 30 06:23:39 2025