5cc1_WX : 3D-footprint complex

structure name	S425G GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - (+)GRE COMPLEX
reference	Ortlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5e69_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cc1_W interface=26,27,31, ppklclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlear > 5cc1_X interface=25,26,30, pklclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=4.960 IC/col=0.382 n_of_columns=13

specificity:

A |   9  24  24   0  75  24  24  24   7   0  24  24   7
C |   7  24  24  96   7  24  24  24   7   0  24  24  73
G |  73  24  24   0   7  24  24  24   9  96  24  24   9
T |   7  24  24   0   7  24  24  24  73   0  24  24   7

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updated Tue Sep 10 02:56:14 2024