5cc1_WX : 3D-footprint complex

structure name	S425G GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - (+)GRE COMPLEX
reference	Ortlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5e69_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cc1_W interface=26,27,31, ppklclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlear > 5cc1_X interface=25,26,30, pklclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=6.560 IC/col=0.505 n_of_columns=13

specificity:

A |   9  24  24   0  96  24  24  24  11   0   9  24   9
C |   1  24  24  96   0  24  24  24   9   0  11  24  76
G |  86  24  24   0   0  24  24  24   9  96   9  24   0
T |   0  24  24   0   0  24  24  24  67   0  67  24  11

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updated Wed Jul 30 06:24:28 2025