5e69_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - IL8 NF-KB RESPONSE ELEMENT COMPLEX
reference	Ortlund et al. 'Nat 9 1337 2018
source	Homo sapiens
experiment	X-ray (resolution=1.85, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5e69_A interface=25,26,30, pklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea > 5e69_B interface=26,30, pklclvcsdeasgchygvltcgsckVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/VR

Estimated binding specificities ?

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# IC=5.163 IC/col=0.516 n_of_columns=10

specificity:

A |   0  20  24  24  24  96  96  15  24   5
C |  96  25  24  24  24   0   0  25  24   6
G |   0  46  24  24  24   0   0  21  24   0
T |   0   5  24  24  24   0   0  35  24  85

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updated Thu Jun 25 03:35:08 2026