5e6a_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - PLAU NF-KB RESPONSE ELEMENT COMPLEX
reference	Ortlund et al. 'Nat 9 1337 2018
source	Homo sapiens
experiment	X-ray (resolution=2.20, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5e69_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5e6a_A interface=25,26,30, pklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea > 5e6a_B interface=30, pklclvcsdeasgchygvltcgsckvffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/R

Estimated binding specificities ?

contact

# IC=5.105 IC/col=0.510 n_of_columns=10

specificity:

A |   0  96  24  24  24  87  69   8  24   8
C |  96   0  24  24  24   0   8   8  24  69
G |   0   0  24  24  24   1  11  11  24   8
T |   0   0  24  24  24   8   8  69  24  11

scan!

home
updated Tue Sep 10 03:43:53 2024