5e6b_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - RELB NF-KB RESPONSE ELEMENT COMPLEX
reference	Ortlund et al. 'Nat 9 1337 2018
source	Homo sapiens
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5e69_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5e6b_A interface=26,27,31, ppklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea > 5e6b_B interface=30, pklclvcsdeasgchygvltcgsckvffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/R

Estimated binding specificities ?

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# IC=5.067 IC/col=0.507 n_of_columns=10

specificity:

A |   0   0  24  24  24  88  72   8  24   8
C |  96   0  24  24  24   8   8   8  24  72
G |   0  88  24  24  24   0   8   8  24   8
T |   0   8  24  24  24   0   8  72  24   8

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updated Wed Jul 30 07:15:17 2025