interface graph thumbnail
legend  pdf

structure nameGLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - CCL2 NF-KB RESPONSE ELEMENT COMPLEX
referenceOrtlund et al. 'Nat 9 1337 2018
sourceHomo sapiens
experimentX-ray (resolution=2.20, R-factor=?)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
reference complex5e69_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVRR/VFA

Estimated binding specificities ?

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# IC=6.339 IC/col=0.792 n_of_columns=8 specificity:   
A |  96  96   6  24   9   0   0  61
C |   0   0  16  24   6  84  96  13
G |   0   0   6  24   6   6   0  16
T |   0   0  68  24  75   6   0   6
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updated Wed Jul 30 07:15:24 2025