5ejk_ABG : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ROUS SARCOMA VIRUS INTASOME
reference	Banerjee et al. Nature 530 362 2016
source	ROUS SARCOMA VIRUS (STRAIN PRAGUE C) / ROUS SARCOMA VIRUS (STRAIN PRAGUE C) / ROUS SARCOMA VIRUS (STRAIN PRAGUE C) / ROUS SARCOMA VIRUS (STRAIN PRAGUE C) / ROUS SARCOMA VIRUS (STRAIN PRAGUE C) / ROUS SARCOMA VIRUS (STRAIN PRAGUE C)
experiment	X-ray (resolution=3.80, R-factor=?)
structural superfamily	Ribonuclease H-like;DNA-binding domain of retroviral integrase;N-terminal Zn binding domain of HIV integrase;
reference complex	7jn3_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5ejk_A interface=154,157,158,161,203,244, plreakdlhtalhigpralskasnismqqarevvqtcphcnsapaleagvnprglgplqiwqtdftleprmaprswlavtvdtassaivvtqhgrvtsvavqhhwataiavmgrpkaiktdngscftskstrewmarwgiahttgipgnsqgqAmvERanRmmkdkirvlaegdgfmkriptskqgemmakamyalnhfergEntktpiqkhwrptvltegppvkirietgewekgwnvlvwgRgyaavknrdtdkviwvpsrkvkpdi > 5ejk_B interface= plreakdlhtalhigpralskasnismqqarevvqtcphcplqiwqtdftleprmaprswlavtvdtassaivvtqhgrvtsvavqhhwataiavmgrpkaiktdngscftskstrewmarwgiahttgipgnsqgqamveranrmmkdkirvLaeGDgfMkriptskqgemmakamyalnhfergentktpiqkhwrptvlTegppvkirietgewekgwnvlvwgrgyaavknrdtdkviwVpsrkvkpdi > 5ejk_G interface=244, plreakdlhtalhigpralskasnismqqarevvqtcphcprglgplqiwqtdftleprmaprswlavtvdtassaivvtqhgrvtsvavqhhwataiavmgrpkaiktdngscftskstrewmarwgiahttgamveranrmmkdkirvlaegdgfmkriptskqgemmakamyalnhfergentktpiqkhwrptvltegppvkirietgewekgwnvlvwgrgyaavknrdtdkviwvpsRkvkpdi
interface signature	AERRER/LGDMTV/R

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |  13  13   0   0   0
C |  16  13   0   0   0
G |  54  16   0  96   0
T |  13  54  96   0  96

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updated Mon Jan 5 16:11:21 2026