5fw1_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SPYCAS9 VARIANT VQR BOUND TO SGRNA AND TGAG PAM TARGET DNA (CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
reference	Bargsten et al. Mol.Cell 61 895 2016
source	STREPTOCOCCUS PYOGENES
experiment	X-ray (resolution=2.50, R-factor=0.220)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5fw1_B interface=1058,1170,1273,1275,1277, kysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdsvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarnsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdgkatakyffysnimnffkteikrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfvsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylasheqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkQyRstkevldatlihqsitglyetridlsq
interface signature	KERQR

Estimated binding specificities ?

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# IC=3.744 IC/col=0.936 n_of_columns=4

specificity:

A |  13   0  95   3
C |  13   0   1   5
G |  12  96   0  84
T |  58   0   0   4

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updated Fri Jan 9 03:21:13 2026