interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SPYCAS9 VARIANT VQR BOUND TO SGRNA AND TGAG PAM TARGET DNA
(CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
referenceBargsten et al. Mol.Cell 61 895 2016
sourceSTREPTOCOCCUS PYOGENES
experimentX-ray (resolution=2.50, R-factor=0.220)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERQR

Estimated binding specificities ?

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# IC=3.744 IC/col=0.936 n_of_columns=4 specificity:   
A |  13   0  95   3
C |  13   0   1   5
G |  12  96   0  84
T |  58   0   0   4
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updated Thu Sep 12 21:17:52 2024