interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SPCAS9 VARIANT EQR BOUND TO SGRNA AND TGAG PAM TARGET DNA
(CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
referenceBargsten et al. Mol.Cell 61 895 2016
sourceSTREPTOCOCCUS PYOGENES
experimentX-ray (resolution=2.68, R-factor=0.206)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERQR

Estimated binding specificities ?

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# IC=3.555 IC/col=0.889 n_of_columns=4 specificity:   
A |  20   0  76   0
C |  19   0   0   0
G |  19  96   0  96
T |  38   0  20   0
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updated Fri Jan 9 03:21:42 2026