5fw2_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SPCAS9 VARIANT EQR BOUND TO SGRNA AND TGAG PAM TARGET DNA (CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
reference	Bargsten et al. Mol.Cell 61 895 2016
source	STREPTOCOCCUS PYOGENES
experiment	X-ray (resolution=2.68, R-factor=0.206)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5fw2_B interface=1068,1180,1284,1286,1288, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarknsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdgkatakyffysnimnffkteitkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfesptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkQyRstkevldatlihqsitglyetridlsql
interface signature	KERQR

Estimated binding specificities ?

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# IC=3.569 IC/col=0.892 n_of_columns=4

specificity:

A |   0  19   0  38
C |  96   0  96  20
G |   0   0   0  19
T |   0  77   0  19

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updated Thu Sep 12 21:18:17 2024