5fw3_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SPCAS9 VARIANT VRER BOUND TO SGRNA AND TGCG PAM TARGET DNA (CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
reference	Bargsten et al. Mol.Cell 61 895 2016
source	STREPTOCOCCUS PYOGENES
experiment	X-ray (resolution=2.70, R-factor=0.216)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5fw3_B interface=1074,1186,1290,1292,1294, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarensrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdeigkatakyffysnimnffkteitlaeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfvsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasarElqkgnelalpskyvnflylashneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkEyRstkevldatlihqsitglyetridlsql
interface signature	KERER

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4

specificity:

A |  16   0  13   0
C |  13   0  54   0
G |  13  96  16  96
T |  54   0  13   0

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updated Fri Jan 9 03:22:13 2026