interface graph thumbnail
legend  pdf

structure nameHUMAN TOPOISOMERASE IIALPHA IN COMPLEX WITH DNA AND ETOPOSIDE
(DNA topoisomerase 2-alpha)
referenceWang et al. 'Nucleic 45 10861 2017
sourceHomo sapiens
experimentX-ray (resolution=3.15, R-factor=0.205)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
reference complex4fm9_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Mon Dec 18 12:51:57 2023