interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ALPHA IN BINARY COMPLEX WITH A DNA:DNA TEMPLATE- PRIMER
(DNA polymerase alpha catalytic subunit)
referenceAggarwal et al. 'Sci 6 23784 2016
sourceHomo sapiens
experimentX-ray (resolution=3.30, R-factor=0.185)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B; DNA polymerase family B, exonuclease do;
multimeric complexes8d0b_ABF
reference complex8d0b_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYTKR

Estimated binding specificities ?

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# IC=2.660 IC/col=0.665 n_of_columns=4 specificity:   
A |   7   1  14  73
C |  81  88   7   9
G |   8   7  22   7
T |   0   0  53   7
scan!

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updated Sat Aug 2 08:56:00 2025