3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Wed Sep 11 21:49:24 2024

structure name	HUMAN CST-DNA POLYMERASE ALPHA/PRIMASE PREINITIATION COMPLEX BOUND TO 4XTEL-FOLDBACK TEMPLATE
source	HOMO SAPIENS
experiment	NMR
structural superfamily	"Winged helix" DNA-binding domain;Nucleic acid-binding proteins;Ribonuclease H-like;DNA/RNA polymerases;Zinc finger domain of DNA polymerase-alpha;
reference complex	8d0b_A 8d0b_B 8d0b_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8d0b_A interface=849,851,872,874,898,902,904,906,908,910,958,997,999,1006,1008,1043,1047,1076,1079,1087,1089,1091,1105,1107, psseqawledaqvfiqktlcpavkepnvqltplvidcvktvwlsqgrnqgstlplsysfvsvqdlkthqrlpccshlswsssayqawaqeagpngnplpreqllllgtltdlsadleqecrngslyvrdntgvlscelidldlswlghlflfprwsylpparwnssgeghlelwdapvpvfpltispgpvtpipvlypesascllrlrnklrgvqrnlagslvrlsalvkskqkayfilslgrshpavthvsiivqvpaqlvwhralrpgtayvltelrvskirgqrqhvwmtsqssrllllkpecvqevrysrllsysgavtgvlnepaglyeldgqlglclayqqfrglrrvmrpgvclqlqdvhllqsvgggtrrpvlapclrgavllqsfsrqkpgahssrqaygaslyeqlvwerqlglplylwatkaleelacklcphvlrhhqflqhsspgspslglqllaptldllappgspvrnahneileephhcplqkytrlqtpssfptlatlkeegqrkawasfdpkallplpeasylpscqlnrrlawswlcllpsafcpaqvllgvlvasshkgclqlrdqsgslpclllakhsqplsdprligclvraerfqliverdvrssfpswkelsmpgfiqkqqarvyvqffladalilpvprpgqsrlfllchkealmkrnfcvppgaspevpkpalsfyvlgswlggtqrkegtgwglpepqgnddndqkvhliffgssvrwfeflhpgqvyrlvapgpatpmlfekdgsscisrrplelagcascltvqdnwtlelessqdiqdvldankslpessltdllsdnftdslvsfsaeilsrtlcepRrCvkltvaletaecefpphldvYiEdphlppslgllpgarvhfsqlekRvsrShNvYcCfRsstyvqvlsfppettisvplphiylaellqggqspfqataschivsvFslqlfwvcayctsicrqgkctrlgstcptqtaisqaiiRlLvedgtaEaVvtcrnhhvaaalglcprewaslldfvqvpgrvvlQfagPepmtmflwtlctspsvlrpivlsfelerKpsKivpleppRlQrFqcgelpflthvnpRlRlsclsires > 8d0b_B interface=18,66,83,135,140,142, rceeetpsllwgldpvfLafaklyirdildmkesrqvpgvflynghpikqvdvlgtvigvrerdaFysygvddstgvincicWkklntesvsaapsaarelsltsqlkklqetieqktkieigdtirvrgsirtYreerEiHattyykvddpvwniqiarmlelptiyrkvydqpfhssalekeealsnpgaldlpsltsllsekakeflmenrvqsfyqqelemvesllslanqpvihsassdqvnfkkdttskaihsifknaiqllqekglvfqkddgfdnlyyvtredkdlhrkihriiqqdcqkpnhmekgchflhilacarlsirpglseavlqqvlelledqsdivstmehyytaf > 8d0b_F interface=231,330,331,332,349, vdsshlplvkgadeeqvfhfywldayedqynqpgvvflfgkvwiesaethvsccvmvkniertlyflpremkidlntgketgtpismkdvyeefdekiatkykimkfkskpveknyafeipdvpekseylevkysaempqlpqdlkgetfshvfgtntsslelflmnrkikgpcwlevkspqllnqpvswckveamalkpdlvnvikdvsppplvvmafsmktmqnaknhQneiiamaalvhhsfaldkaapkppfqshfcvvskpkdcifpyafkeviekknvkvevaatertllgfflakvhkidpdiivghniygfelevllqrinVCKaphwskigrlkrsnmpKlggrsgfgernatcgrmicdveisakelircksyhlselvqqilktervvipmeniqnmysessqllyllehtwkdakfilqimcelnvlplalqitniagnimsrtlmggrserneflllhafyennyivpdkqglvldpkvgfydkfillldfnslypsiiqefnicfttvqrvaseaqkvtedgeqeqipelpdpslemgilpreirklverrkqvkqlmkqqdlnpdlilqydirqkalkltansmygclgfsysrfyakplaalvtykgreilmhtkemvqkmnleviygdtdsimintnstnleevfklgnkvksevnklyklleididgvfksllllkkkkyaalvveptsdgnyvtkqelkqltdeekyrdcerfkcpcptcgteniydnvfdgsgtdmepslyrcsnidckaspltftvqlsnklimdirrfikkyydgwliceeptcrnrtrhlplqfsrtgplcpacmkatlqpeysdkslytqlcfyryifdaecaleklttdhekdklkkqfftpkvlqdyrklkntaeqflsrsgysevnlsklfagcavks