interface graph thumbnail
legend  pdf

structure name1.98A STRUCTURE OF GSK945237 WITH S.AUREUS DNA GYRASE AND SINGLY NICKED DNA
referenceMiles et al. Bioorg.Med.Chem.Lett. 26 2464 2016
sourceSTAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experimentX-ray (resolution=1.98, R-factor=?)
structural superfamilyType II DNA topoisomerase;
reference complex5iwi_C 5iwi_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYSI/K

Estimated binding specificities ?

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# IC=2.379 IC/col=0.476 n_of_columns=5 specificity:   
A |  20  19  24   2   2
C |  38  19  24  92   1
G |  19  20  24   1  92
T |  19  38  24   1   1
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updated Wed Jul 30 08:39:47 2025