interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) ZNF2-4 Q369H IN COMPLEX WITH FORMYLATED DNA
(Wilms tumor protein)
referenceHashimoto et al. 'Nucleic 44 10165 2016
sourceHomo sapiens
experimentX-ray (resolution=1.78, R-factor=0.218)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDHRRDHTRDER

Estimated binding specificities ?

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# IC=9.298 IC/col=1.033 n_of_columns=9 specificity:   
A |   9   0   9   0   0   0   0   0   9
C |  11  96  11   0   0   0   0   0   9
G |  67   0  67   0  96  96  96  96  11
T |   9   0   9  96   0   0   0   0  67
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updated Thu Sep 12 21:43:18 2024