5lek_AB : 3D-footprint complex

structure name	THE TRANSCRIPTIONAL REGULATOR PRFA-G145S MUTANT FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH A 30-BP OPERATOR PRFA-BOX MOTIF
reference	Sauer-Eriksson et al. 'Proc. 113 14733 2016
source	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) / Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) / Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) / Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	cAMP-binding domain-like;"Winged helix" DNA-binding domain;
reference complex	5lej_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5lek_A interface=181,183,184,186,187, naqaeefkkyletngikpkqfhkkelifnqwdpqeyciflydgitkltsisengtimnlqyykgafvimsgfidtetsvgyynleviseqatayvikinelkellsknlthffyvfqtlqkqvsyslakfndfsingklgsicsqlliltyvygketpdgikitldnltmqelgyssgiaHsSAvSRiisklkqekvivyknscfyvqnldylkryapkldewfylacpatwgkln > 5lek_B interface=181,183,184,186,187, naqaeefkkyletngikpkqfhkkelifnqwdpqeyciflydgitkltsisengtimnlqyykgafvimsgfidtetsvgyynleviseqatayvikinelkellsknlthffyvfqtlqkqvsyslakfndfsingklgsicsqlliltyvygketpdgikitldnltmqelgyssgiaHsSAvSRiisklkqekvivyknscfyvqnldylkryapkldewfylacpatwgkln
interface signature	HSASR/HSASR

Estimated binding specificities ?

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# IC=7.625 IC/col=0.762 n_of_columns=10

specificity:

A |  73  96   0  73  24  24   7   0   0   7
C |   7   0  96   9  24  24   7   0   0   7
G |   9   0   0   7  24  24   9  96   0   7
T |   7   0   0   7  24  24  73   0  96  75

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updated Wed Jul 30 09:43:31 2025