interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD4-MH1 BOUND TO THE GGCT SITE.
(MH1 domain of human Smad4)
referenceKaczmarska et al. 'Nat 8 2070 2017
sourceHomo sapiens
experimentX-ray (resolution=2.98, R-factor=0.218)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQK

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5 specificity:   
A |   0  12   0   0  60
C |   0  12  96   0  12
G |  84  60   0   0  12
T |  12  12   0  96  12
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updated Tue Dec 17 02:17:43 2024