interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD4-MH1 BOUND TO THE GGCT SITE.
(MH1 domain of human Smad4)
referenceKaczmarska et al. 'Nat 8 2070 2017
sourceHomo sapiens
experimentX-ray (resolution=2.98, R-factor=0.218)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3qsv_AD 3qsv_BC
reference complex5mey_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQK

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5 specificity:   
A |  12  96   0  12   0
C |  12   0   0  60  84
G |  12   0  96  12  12
T |  60   0   0  12   0
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updated Thu Sep 12 21:48:25 2024