interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD4-MH1 BOUND TO THE GGCGC SITE.
(MH1 domain of human Smad4)
referenceKaczmarska et al. 'Nat 8 2070 2017
sourceHomo sapiens
experimentX-ray (resolution=2.05, R-factor=0.223)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3qsv_AD 3qsv_BC
redundant complexes3qsv_D 5mez_A 5mf0_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SMAD4
GTCTAGACPubMed3qsv_AD(2.44e-14), 3qsv_BC(6.88e-15), 5mez_A(1.02e-02), ... (total=4)
CAGACPubMed3qsv_AD(2.42e-03), 3qsv_BC(1.79e-03), 3qsv_A(1.72e-04)

Dendrogram of similar interfaces ?

matrix format
  
  --RGQC--KG   L              +5nm9_A    
                            +-1 
  DCRGQC--KG   L   +--------3 +6tbz_A    
                   !        ! 
  --RGQA--KA   L   !        +6h3r_A    
                 --5 
  DCRGQC--KG   L   !       +-6fzt_A    
                   +-------4 
  --RGQAHTKG   L           ! +5x6g_A    
                           +-2 
  DCRGQC--KG   L             +6zmn_B    
                 

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updated Fri Sep 13 20:00:52 2024