5n8s_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DROSOPHILA DHX36 HELICASE IN COMPLEX WITH POLYT (CG9323, isoform A)
reference	Hai-Lei Guo et al. Structure 26 403 2018
source	Drosophila melanogaster
experiment	X-ray (resolution=2.88, R-factor=0.211)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	Helicase associated domain HA2; Domain of unknown function DUF1605; Helicase conserved Cterminal domain;
reference complex	5n8r_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5n8s_A interface=178,200,201,203,204,359,392,440,451,560,562,591,592,598,603,607,667,714,730,731,732,752, irlgcnvsapsgvlervkelmedysrapdakfqqqfrhllsvnfeefvaetkernadldwvnpklderlqlelgqrqleenakkrlearkklptmkyaddiiqavrenqvilivgstgcgkttqvpqillddaisrgcasscriictqprrisaiaiaewvsyerceslgnsvgyqiRlesrkarerasitycttgvllQQlQSdplmhnlsvlildeihersvetdllmgllkvilphrpdlkvilmsatvreqdfcdyfnncpmfriegvmfpvkmlyledvlsktnyefqkrrmkheamiepylrrirnsydsrvldklrlpesegcedidfiadlvyyicenepegailvflpgYdkisqlynildkpktskgqrwrdhmavfplhsLmqsgeqqavfrrppagqrkviistiiaetsvtiddvvyvinsgrtkaTnydietniqsLdevwvtkantqqrrgragrvrpgicynlfsraredrmddiptpeilrsklesiilslkllhiddpyrflqtlinapnpeaikmgvellkriealdqtgtltplgmhlaKlPidpqmgkmilmsalfccldpitsaaaalSFkspfySplgkEsrvDeikrrmarnmrsdhlmvhntiiayrdsryshaerdfcyknflssmtlqqlermknqfseLlynykflassnckdaasnknsekipllraiigaglypnmahlrksrRaihtmatddgrrvnfHPSsvnsgesgfdsayfvyfqrQkstdlflldstmvfpmaliifgdgveagvtqntpylcvaktyyfkcnretadvviqlrsnleklllkkalypapieengyekqlikaielllslderl
interface signature	RQQQSYLTLKPSFSEDLRHPSQ

Estimated binding specificities ?

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# IC=8.909 IC/col=0.891 n_of_columns=10

specificity:

A |   0   0   0   0  24  24  12   0   0   7
C |   0   0   0   0  24  24  12   0   0   7
G |   0   0   0   0  24  24  12   0   0   7
T |  96  96  96  96  24  24  60  96  96  75

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updated Thu Sep 12 21:50:19 2024