5n90_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DROSOPHILA DHX36 HELICASE IN COMPLEX WITH TTGTGGTGT (CG9323, isoform A)
reference	Chen et al. Structure 26 403 2018
source	Drosophila melanogaster
experiment	X-ray (resolution=3.07, R-factor=0.189)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	Helicase associated domain HA2; Domain of unknown function DUF1605; Helicase conserved Cterminal domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5n90_B interface=178,200,201,203,204,225,358,359,391,416,436,439,450,494,497,502,561,563,590,591,597,602,606,713,729,730,731, irlgcnvsapsgvlervkelmedysrapdakfqqqfrhllsvnfeefvaetkernadldwvnpklderlqlelgqrqleenakkrlearkklptmkyaddiiqavrenqvilivgstgcgkttqvpqillddaisrgcasscriictqprrisaiaiaewvsyerceslgnsvgyqiRlesrkarerasitycttgvllQQlQSdplmhnlsvlildeihersvEtdllmgllkvilphrpdlkvilmsatvreqdfcdyfnncpmfriegvmfpvkmlyledvlsktnyefqkrmkheamiepylrrirnsydsrvldklrlpesegcedidfiadlvyyicenepegailvflpgYDkisqlynildkpktskgqrwrdhmavfplhsLmqsgeqqavfrrppagqrkviistIiaetsvtiddvvyvinsgrTkaTnydietniqsLdevwvtkantqqrrgragrvrpgicynlfsraredrmddiptpEilRskleSiilslkllhiddpyrflqtlinapnpeaikmgvellkriealdqtgtltplgmhlaklPiDpqmgkmilmsalfccldpitsaaaalSFkspfySplgkEsrvDeikrrmarnmrsdhlmvhntiiayrdsryshaerdfcyknflssmtlqqlermknqfsellynykflassnckdaasnknsekipllraiigaglypnmahlrksrRaihtmatddgrrvnfHPSsvnsgesgfdsayfvyfqrqkstdlflldstmvfpmaliifgdgveagvtqntpylcvaktyyfkcnretadvviqlrsnleklllkkalypapieengyekqlikaielllslderl
interface signature	RQQQSEYDLITTLERSPDSFSEDRHPS

Estimated binding specificities ?

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# IC=9.474 IC/col=1.053 n_of_columns=9

specificity:

A |   0   0   0   0   0  21  21   0   0
C |   0   0   0   0   0  21  21   0   0
G |   0   0  96   0  96  44  21  96   0
T |  96  96   0  96   0  10  33   0  96

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updated Tue Dec 17 02:20:18 2024