5n96_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DROSOPHILA DHX36 HELICASE IN COMPLEX WITH AGGGTTTTTT (CG9323, isoform A)
reference	Chen et al. Structure 26 403 2018
source	Drosophila melanogaster
experiment	X-ray (resolution=2.72, R-factor=0.183)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	Helicase associated domain HA2; Domain of unknown function DUF1605; Helicase conserved Cterminal domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5n96_A interface=178,200,201,203,204,358,359,391,439,450,494,497,561,563,590,591,597,602,606,713,729,730,731, irlgcnvsapsgvlervkelmedysrapdakfqqqfrhllsvnfeefvaetkernadldwvnpklderlqlelgqrqleenakkrlearkklptmkyaddiiqavrenqvilivgstgcgkttqvpqillddaisrgcasscriictqprrisaiaiaewvsyerceslgnsvgyqiRlesrkarerasitycttgvllQQlQSdplmhnlsvlildeihersvetdllmgllkvilphrpdlkvilmsatvreqdfcdyfnncpmfriegvmfpvkmlyledvlsktnyefqkrmkheamiepylrrirnsydsrvldklrlpesegcedidfiadlvyyicenepegailvflpgYDkisqlynildkpktskgqrwrdhmavfplhsLmqsgeqqavfrrppagqrkviistiiaetsvtiddvvyvinsgrtkaTnydietniqsLdevwvtkantqqrrgragrvrpgicynlfsraredrmddiptpEilRsklesiilslkllhiddpyrflqtlinapnpeaikmgvellkriealdqtgtltplgmhlaklPiDpqmgkmilmsalfccldpitsaaaalSFkspfySplgkEsrvDeikrrmarnmrsdhlmvhntiiayrdsryshaerdfcyknflssmtlqqlermknqfsellynykflassnckdaasnknsekipllraiigaglypnmahlrksrRaihtmatddgrrvnfHPSsvnsgesgfdsayfvyfqrqkstdlflldstmvfpmaliifgdgveagvtqntpylcvaktyyfkcnretadvviqlrsnleklllkkalypapieengyekqlikaielllslderl
interface signature	RQQQSYDLTLERPDSFSEDRHPS

Estimated binding specificities ?

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# IC=8.431 IC/col=0.937 n_of_columns=9

specificity:

A |  96   0   0   0  24  13  13   0   0
C |   0   0   0   0  24  16  13   0   0
G |   0  96  96  96  24  13  16   0   0
T |   0   0   0   0  24  54  54  96  96

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updated Tue Dec 17 02:20:30 2024