5n9a_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DROSOPHILA DHX36 HELICASE IN COMPLEX WITH GTTAGGGTT (CG9323, isoform A)
reference	Chen et al. Structure 26 403 2018
source	Drosophila melanogaster
experiment	X-ray (resolution=3.04, R-factor=0.220)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	Helicase associated domain HA2; Domain of unknown function DUF1605; Helicase conserved Cterminal domain;
reference complex	5n8r_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5n9a_A interface=178,225,358,391,437,439,450,494,497,561,590,597,602,606,713,729,730,731, irlgcnvsapsgvlervkelmedysrapdakfqqqfrhllsvnfeefvaetkernadldwvnpklderlqlelgqrqleenakkrlearkklptmkyaddiiqavrenqvilivgstgcgkttqvpqillddaisrgcasscriictqprrisaiaiaewvsyerceslgnsvgyqiRlesrkarerasitycttgvllqqlqsdplmhnlsvlildeihersvEtdllmgllkvilphrpdlkvilmsatvreqdfcdyfnncpmfriegvmfpvkmlyledvlsktnyefqkrmkheamiepylrrirnsydsrvldklrlpesegcedidfiadlvyyicenepegailvflpgYdkisqlynildkpktskgqrwrdhmavfplhsLmqsgeqqavfrrppagqrkviistiiaetsvtiddvvyvinsgrtKaTnydietniqsLdevwvtkantqqrrgragrvrpgicynlfsraredrmddiptpEilRsklesiilslkllhiddpyrflqtlinapnpeaikmgvellkriealdqtgtltplgmhlaklPidpqmgkmilmsalfccldpitsaaaalSfkspfySplgkEsrvDeikrrmarnmrsdhlmvhntiiayrdsryshaerdfcyknflssmtlqqlermknqfsellynykflassnckdaasnknsekipllraiigaglypnmahlrksrRaihtmatddgrrvnfHPSsvnsgesgfdsayfvyfqrqkstdlflldstmvfpmaliifgdgveagvtqntpylcvaktyyfkcnretadvviqlrsnleklllkkalypapieengyekqlikaielllslderl
interface signature	REYLKTLERPSSEDRHPS

Estimated binding specificities ?

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# IC=8.302 IC/col=1.038 n_of_columns=8

specificity:

A |   0   0   0  96  12   0  24   0
C |   0   0   0   0  12   0  24   0
G |  96   0   0   0  60  96  24   0
T |   0  96  96   0  12   0  24  96

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updated Mon Dec 18 13:22:14 2023