5n9d_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DROSOPHILA DHX36 HELICASE IN COMPLEX WITH GGGTTAGGGT (CG9323, isoform A)
reference	Chen et al. Structure 26 403 2018
source	Drosophila melanogaster
experiment	X-ray (resolution=2.71, R-factor=0.188)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	Helicase associated domain HA2; Domain of unknown function DUF1605; Helicase conserved Cterminal domain;
reference complex	5n8r_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5n9d_A interface=178,200,201,203,204,358,359,391,439,450,494,502,559,561,563,590,597,602,606,666,719,735,736,737,741, irlgcnvsapsgvlervkelmedysrapdakfqqqfrhllsvnfeefvaetkernadldwvnpklderlqlelgqrqleenakkrlearkklptmkyaddiiqavrenqvilivgstgcgkttqvpqillddaisrgcasscriictqprrisaiaiaewvsyerceslgnsvgyqiRlesrkarerasitycttgvllQQlQSdplmhnlsvlildeihersvetdllmgllkvilphrpdlkvilmsatvreqdfcdyfnncpmfriegvmfpvkmlyledvlsktnyefqkrmkheamiepylrrirnsydsrvldklrlpesegcedidfiadlvyyicenepegailvflpgYDkisqlynildkpktskgqrwrdhmavfplhsLmqsgeqqavfrrppagqrkviistiiaetsvtiddvvyvinsgrtkaTnydietniqsLdevwvtkantqqrrgragrvrpgicynlfsraredrmddiptpEilrskleSiilslkllhiddpyrflqtlinapnpeaikmgvellkriealdqtgtltplgmhlaKlPiDpqmgkmilmsalfccldpitsaaaalSfkspfySplgkEsrvDeikrrmarnmrsdhlmvhntiiayrdsryshaerdfcyknflssmtlqqlermknqfseLlynykflassnckdaasnknsekipllraiigaglypnmahlrksrqiknrvRaihtmatddgrrvnfHPSsvnSgesgfdsayfvyfqrqkstdlflldstmvfpmaliifgdgveagvtqntpylcvaktyyfkcnretadvviqlrsnleklllkkalypapieengyekqlikaielllslderl
interface signature	RQQQSYDLTLESKPDSSEDLRHPSS

Estimated binding specificities ?

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# IC=9.805 IC/col=0.980 n_of_columns=10

specificity:

A |   0   0   0   0  13  96  24   0   0  16
C |   0   0   0   0  13   0  24   0   0  13
G |  96  96  96   0  13   0  24  96  96  13
T |   0   0   0  96  57   0  24   0   0  54

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updated Thu Sep 12 21:51:19 2024