5npk_bd : 3D-footprint complex

structure name	1.98A STRUCTURE OF THIOPHENE1 WITH S.AUREUS DNA GYRASE AND DNA
reference	Stavenger et al. 'Proc. 114 E4492 2017
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=1.98, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5npk_d
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5npk_b interface=42,44,61,210,269,270,277,360, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnnEirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavyanlrinernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvRmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 5npk_d interface=42,44,206,266,303,356, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavyanernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg
interface signature	RKEYSSRI/RKYSRI

Estimated binding specificities ?

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# IC=11.136 IC/col=0.795 n_of_columns=14

specificity:

A |   0   0  12  24   0   0  24  24   0   0  24  24   0   0
C |  96   0  12  24   0   0  24  24  96  96  48  24  96   0
G |   0  96  12  24  96  96  24  24   0   0  12  24   0  96
T |   0   0  60  24   0   0  24  24   0   0  12  24   0   0

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updated Wed Jul 30 10:05:45 2025