5u91_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TRE/LOXLTR COMPLEX
reference	Karpinski et al. 'Nucleic 45 9726 2017
source	synthetic construct
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	DNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
reference complex	5u91_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5u91_E interface=25,26,29,32,71,72,75,79,226,228,229,242,244,245,247,248,267, alpaddevrknlmdvfrdrpafseHTweMllSvcrswaawcklnnrkwfpaepedvrdyllhlqarglavKTiqQhlcRlnmlhrrsglprpsdsnavslvmrrirkenvdagertkqalafertdfdqvrslmensdrcqdirnlaflgvayntllriaeiarirvkdisrtdggrmlihigrtktlvstagvekalslgvtklverwisvsgvaddpnnylfcRvRRygvaapsatsqlStYAlQRifeathrliygakddsgqRylawsghsarvgaardmaragvsipeimqaggwttvnsvmnfirnldsetgamvrlled > 5u91_F interface=19,20,22,23,26,65,66,68,69,72,73,180,220,222,223,224,236,238,241,261, evrknlmdvfrdrpafseHTwEMllSvcrswaawcklnnrkwfpaepedvrdyllhlqarglavKTiQQhlCRlnmlhrrsglprpsdsnavslvmrrirkenvdagertkqalafertdfdqvrslmensdrcqdirnlaflgvayntllriaeiarirvkdisrtdggrmlihigrtKtlvstagvekalslgvtklverwisvsgvaddpnnylfcRvRRYgvaapsatsqlStYalQrifeathrliygakddsgqRylawsghsarvgaardmaragvsipeimqaggwttvnsvmnfirnldsetgamvrlled
interface signature	HTMSKTQRRRRSYAQRR/HTEMSKTQQCRKRRRYSYQR

Estimated binding specificities ?

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# IC=32.016 IC/col=0.942 n_of_columns=34

specificity:

A |   4  82   0  80  24  24  67   0   0   0   0  96   0   0  96   6  81  24  24  24  24  96   0  96   0   0   0   0  96  96  11  84   1   0
C |   1   5  92   3  24  24   9   0  96  96   0   0   0   0   0  80   5  24  24  24  24   0   0   0   0   0  96  96   0   0  65   3   4   0
G |  90   6   1   5  24  24  11   0   0   0   0   0   0   0   0   5   5  24  24  24  24   0   0   0   0  96   0   0   0   0  11   3   1  96
T |   1   3   3   8  24  24   9  96   0   0  96   0  96  96   0   5   5  24  24  24  24   0  96   0  96   0   0   0   0   0   9   6  90   0

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updated Mon Jan 5 22:19:44 2026