interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR (COMPOUND 18)
(INTEGRASE)
reference'Bioorg. 27 2038 2017
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.85, R-factor=0.184)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERP

Estimated binding specificities ?

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# IC=2.299 IC/col=0.575 n_of_columns=4 specificity:   
A |   2   8   9  48
C |   1   7  67  16
G |  92   7   9  16
T |   1  74  11  16
scan!

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updated Tue Dec 17 02:36:13 2024