interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR (COMPOUND 31)
(INTEGRASE)
reference'Bioorg. 27 2038 2017
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.61, R-factor=0.200)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERP

Estimated binding specificities ?

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# IC=2.465 IC/col=0.616 n_of_columns=4 specificity:   
A |   0   7  10  45
C |   0   7  66  16
G |  96   7  10  19
T |   0  75  10  16
scan!

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updated Tue Dec 17 02:36:23 2024