5wti_Z : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE CRISPR-ASSOCIATED PROTEIN IN COMPLEX WITH CRRNA AND DNA (CRISPR-ASSOCIATED PROTEIN)
reference	Huang et al. 'Cell 27 705 2017
source	BACILLUS THERMOAMYLOVORANS
experiment	X-ray (resolution=2.68, R-factor=0.218)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5wti_Z interface=114,115,118,122,138,140,214,217,388,389, matrsfilkiepneevkkglwkthevlnhgiayymnilklirqeaiyehheqdpknpkkvskaeiqaelwdfvlkmqkcnsfthevdkdvvfnilrelyeelvpssvekkgeaNQlsNkflYplvdpnsqsgkgtasSgRkprwynlkiagdpsweeekkkweedkkkdplakilgklaeygliplfipftdsnepivkeikwmeksrnqsvrRldKdmfiqalerflsweswnlkvkeeyekvekehktleerikediqafksleqyekerqeqllrdtlntneyrlskrglrgwreiiqkwlkmdenepsekylevfkdyqrkhpreagdysvyeflskhpeypylyatfceidkkkkdakqqatftladpinhplwvrfeersgSNlnkyrilteqlhteklkkkltvqldrliyptesggweekgkvdivllpsrqfynqifldieekgkhaftykdesikfplkgtlggarvqfdrdhlrryphkvesgnvgriyfnmtvnieptespvskskeltewikdskgkklksgiesleiglrvmsidlgqrqaaaasifevvdqkpdiegklffpikgtelyavhrasfniklpgetlvksrevlrkarednlklmnqklnflrnvlhfqqditerekrvtkwisrqenliqirelmykpykdwvaflkqlhkrleveigkevkhwrkslsdgrkglygislknideidrtrkfllrwslrptepgevrrlepgqrfaidqlnhlnalkedrlkkmantiimhalgycydvrkkkwqaknpacqiilfedlsnynpyeersrfensklmkwsrreiprqvalqgeiyglqvgevgaqfssrfhaktgspgircsvvtkeklqdlypdkggekfislskdrklvtthadinaaqnlqkrfwtrthgfykvyckakiieefgegyfilkdkdsfdlaselkgeklmlyrdpsgnvfpsdkwmaagvffgkleriliskltnq
interface signature	NQNYSRRKSN

Estimated binding specificities ?

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# IC=2.603 IC/col=0.651 n_of_columns=4

specificity:

A |  40   1   0  22
C |  18  19   1  67
G |  19   0   2   3
T |  19  76  93   4

scan!

Dendrogram of similar interfaces ?

matrix format

  
  TGSGNGQCNGYTSTRADCDC--RG--SC--WCRALATANADT--SANARGTG----VARTMT   L        +------------------------5wti_Z    
                                                                         +--1 
  IT----------------------------------------QG------------------       +-2  +------------------------6lu0_A    
                                                                       ! ! 
  --------------------QT--LT--KC--------------------------------   L --3 +---------------------------7lyt_A    
                                                                       ! 
  ------------------------------------------------RGTAECNC------   L   +----------------------------7way_A

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updated Fri Sep 13 20:51:52 2024