interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXA2 DNA BINDING DOMAIN BOUND TO A FULL CONSENSUS DNA SITE
(Hepatocyte nuclear factor 3-beta)
referenceJiang et al. Biochemistry 56 3745 2017
sourceHomo sapiens
experimentX-ray (resolution=2.80, R-factor=0.243)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
reference complex7yze_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSFK

Estimated binding specificities ?

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# IC=5.339 IC/col=0.890 n_of_columns=6 specificity:   
A |   0  96  96  69   9  67
C |   0   0   0   9  67   9
G |   0   0   0   9   9   9
T |  96   0   0   9  11  11
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updated Mon Dec 18 13:52:10 2023