5x6m_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
reference	Wang et al. 'Nucleic 43 9051 2015
source	Mus musculus
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	SMAD MH1 domain;
reference complex	6fzs_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5x6m_A interface=62,64,66,71, spavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrves > 5x6m_B interface=61,63,65,70, pavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrvesp
interface signature	DRQK/DRQK

Estimated binding specificities ?

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# IC=10.630 IC/col=0.886 n_of_columns=12

specificity:

A |   0  11   0   0  11  24  24  96   0   0   0   9
C |   0   9  96  96   9  24  24   0   0   0  96   9
G |   0  67   0   0  67  24  24   0  96   0   0  11
T |  96   9   0   0   9  24  24   0   0  96   0  67

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updated Wed Jul 30 13:45:29 2025