interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD5-MH1 BOUND TO THE GGCGC SITE.
(Mothers against decapentaplegic homolog 5)
referenceKaczmarska et al. 'Computational 19 ? 2021
sourceHomo sapiens
experimentX-ray (resolution=2.31, R-factor=0.195)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB 6fzt_AB
redundant complexes3kmp_A 5x6g_A 5x6h_B 5x6m_F 6fzt_B 6tce_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRQK

Estimated binding specificities ?

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# IC=4.474 IC/col=0.895 n_of_columns=5 specificity:   
A |  60   0  12   0   0
C |  12   0  24  96   0
G |  12  96  12   0  96
T |  12   0  48   0   0
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updated Tue Dec 19 12:54:20 2023