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legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD5-MH1 BOUND TO THE GGCGC SITE.
(Mothers against decapentaplegic homolog 5)
referenceKaczmarska et al. 'Computational 19 ? 2021
sourceHomo sapiens
experimentX-ray (resolution=2.31, R-factor=0.195)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB
redundant complexes3kmp_A 5x6g_A 5x6h_B 5x6m_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRQK

Estimated binding specificities ?

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# IC=4.541 IC/col=0.908 n_of_columns=5 specificity:   
A |  41   0   0   0   0
C |  13   0  13  96   0
G |  13  96  27   0  96
T |  29   0  56   0   0
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updated Sat Jan 10 10:11:22 2026