5x6m_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
reference	Wang et al. 'Nucleic 43 9051 2015
source	Mus musculus
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	SMAD MH1 domain;
reference complex	6fzs_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5x6m_E interface=61,63,65,70, pavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrves > 5x6m_F interface=61,63,65,70, pavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrves
interface signature	DRQK/DRQK

Estimated binding specificities ?

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# IC=8.955 IC/col=0.746 n_of_columns=12

specificity:

A |  96   0  81   0  24  24  24  16   0  14   7  89
C |   0   0   1  96  24  24  24  59   0   7  88   0
G |   0  96  14   0  24  24  24  14  96  59   1   7
T |   0   0   0   0  24  24  24   7   0  16   0   0

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updated Mon Jan 5 23:22:43 2026