interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF CTCF ZFS2-8-HS5-1AE
(Transcriptional repressor CTCF)
referenceWang et al. 'Cell 27 1365 2017
sourceHomo sapiens
experimentX-ray (resolution=2.81, R-factor=0.225)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex8sst_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRYESKRTYKRQSTRSDV

Estimated binding specificities ?

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# IC=13.761 IC/col=1.147 n_of_columns=12 specificity:   
A |   0  96  13   0  96   0  54   0   0   0   0   0
C |  96   0  13  96   0   0  16   0   0   0  96   0
G |   0   0  54   0   0  96  13  96  96  96   0  96
T |   0   0  16   0   0   0  13   0   0   0   0   0
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updated Fri Jan 9 05:02:35 2026