5ywt_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TREX1 IN COMPLEX WITH A DUPLEX DNA WITH 3' OVERHANG (Three-prime repair exonuclease 1)
reference	'PLoS 16 e2005653 2018 X-RAY DIFFRACTION
source	Mus musculus
experiment	X-ray (resolution=1.70, R-factor=0.196)
structural superfamily	Ribonuclease H-like;
sequence family	Exonuclease;
multimeric complexes	4ynq_AC 4ynq_BD
redundant complexes	4ynq_D 5yws_A 5ywu_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5ywt_A interface=20,21,74,77,80,121,124,125,153,156,181,204, tlphghmqtlifldleatgLPssrpevtelcllavhrralentsisqghpppvprpprvvdklslciapgkacSpgAseItglskaelevqgrqrfddnlaillraflqrqpqpcclvahNgdRYdfpllqtelarlstpspldgtfcvdsiAalKaleqksyslgsiytrlywqaptdsHtaegdvltllsicqwkpqallqWvdeharpfstvkpmygtp
interface signature	LPSAINRYAKHW

Estimated binding specificities ?

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# IC=5.914 IC/col=1.183 n_of_columns=5

specificity:

A |   0   0   7   0   0
C |  96   0  74   0   0
G |   0   0   7   0   0
T |   0  96   8  96  96

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Dendrogram of similar interfaces ?

matrix format

  
  LTPT--ST--ATITNCRTYT--ACKC----HTWC--   L                               +5ywt_A    
                                                         +---------------1 
  LCPC--SG--AGIGNCRGYC----------------              +----2               +4ynq_A    
                                                    !    ! 
  ----QT------------------------------         +----3    +---------------8d0k_F    
                                               !    ! 
  ----QT------------------------------       +-4    +--------------------8d0b_F    
                                             ! ! 
  MG------ET--VT------------RASA------     --5 +-------------------------5m1s_D    
                                             ! 
  --------------NTNTFCYT--RG--------WG       +---------------------------2xhb_A

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updated Sun Aug 3 10:36:30 2025