5z6z_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO DNA (Double homeobox protein 4)
reference	Gan et al. 'Biochem. 505 1161 2018
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=0.213)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5z6z_A interface=2,5,47,50,51,53,54,68,71,113,116,117,121, gRrrRlvwtpsqsealracfernpypgiatrerlaqaigipeprvqIwfQNeRSrqlrqhrrespegRrkRtavtgsqtalllrafekdrfpgiaareelaretglpesriqIwfQNrraRh
interface signature	RRIQNRSRRIQNR

Estimated binding specificities ?

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# IC=10.842 IC/col=0.903 n_of_columns=12

specificity:

A |   0   0  96   5  24  60   5  90   0   0  96  11
C |   0   0   0  25  24  15  10   0   0   0   0   5
G |   0  96   0   5  24  10  70   5   0   0   0  70
T |  96   0   0  61  24  11  11   1  96  96   0  10

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updated Tue Dec 17 03:10:56 2024