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legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO DNA
(Double homeobox protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.213)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNRSRRIQNR

Estimated binding specificities ?

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# IC=11.007 IC/col=0.917 n_of_columns=12 specificity:   
A |   4   0  96  96   0  11   9  24  64   0   0  96
C |  81   0   0   0   4  52  14  24   4   0  96   0
G |   7   0   0   0   0  24  11  24  24   0   0   0
T |   4  96   0   0  92   9  62  24   4  96   0   0
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updated Sat Aug 2 10:11:48 2025