interface graph thumbnail
legend  pdf

structure nameHUMAN TOPOISOMERASE II BETA IN COMPLEX WITH DNA
(DNA topoisomerase 2-beta)
referenceTang et al. 'Sci 8 14949 2018
sourceHomo sapiens
experimentX-ray (resolution=2.54, R-factor=0.183)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
multimeric complexes4g0u_AB 4g0v_AB 4g0w_AB
reference complex3qx3_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKAIA

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0   0  24  13  16
C |  96   0  24  13  54
G |   0  96  24  54  13
T |   0   0  24  16  13
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updated Mon Dec 18 14:15:53 2023