interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE CRTC2-CREB-CRE COMPLEX
referenceValecia-Swain et al. 'J. 430 1926 2018
experimentX-ray (resolution=3.05, R-factor=0.244)
structural superfamilyLeucine zipper domain;
sequence familybZIP transcription factor; Basic region leucine zipper;
multimeric complexes1dh3_AC 5zk1_AC 5zko_ACGH
reference complex1dh3_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRACR

Estimated binding specificities ?

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# IC=3.968 IC/col=0.794 n_of_columns=5 specificity:   
A |   9   9  96  11   0
C |   9   9   0  67   0
G |  11  67   0   9  96
T |  67  11   0   9   0
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updated Fri Jan 9 05:17:35 2026