6aeb_F : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF XCAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (AAG PAM) (DNA Nuclease)
reference	Huang et al. 'Cell 29 183 2019
source	Streptococcus pyogenes
experiment	X-ray (resolution=3.00, R-factor=0.232)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6aeb_F interface=1068,1289,1291, kysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedtklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmiklydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngiiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfekvvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgdqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfiqlihddsltfkediqkaqslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygkatakyffysnimnffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagvlqkgnelalpskyvnflylashyepedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkRytstkevldatlihqsitglyetridlsqlg
interface signature	KRR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4

specificity:

A |  54   0   0  13
C |  13  96   0  16
G |  13   0   0  13
T |  16   0  96  54

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updated Fri Jan 9 05:23:18 2026