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structure nameI-ONUI K227Y, D236A BOUND TO COGNATE SUBSTRATE (PRE-CLEAVAGE COMPLEX)
(Ribosomal protein 3homing endonuclease-like protein fusion)
referenceMcMurrough et al. 'To ? ? ?
sourceOphiostoma novo-ulmi subsp. americana
experimentX-ray (resolution=1.45, R-factor=0.166)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
redundant complexes3qqy_A 6bdb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSRRNKSSEQTSASKCFNISKQQSTYKYKFWTK

Estimated binding specificities ?

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# IC=21.797 IC/col=1.038 n_of_columns=21 specificity:   
A |  13  24   0   0   0  96   0   0  13  24  24   0   0  96  96   0   0   0   0   0   0
C |  16  24   0  96  96   0  96   0  13  24  24   0  96   0   0  96  96   0   0   0   0
G |  13  24   0   0   0   0   0   0  13  24  24   0   0   0   0   0   0   0   0   0   0
T |  54  24  96   0   0   0   0  96  57  24  24  96   0   0   0   0   0  96  96  96  96
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Dendrogram of similar interfaces ?

matrix format

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updated Sat Jan 10 09:46:06 2026