6c31_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TETR FAMILY PROTEIN RV0078 IN COMPLEX WITH DNA
reference	Hsu et al. MBio 9 ? 2018
source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Homeodomain-like;Tetracyclin repressor-like, C-terminal domain;
reference complex	6c31_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6c31_A interface=3,33,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtPeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_B interface=3,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtpeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_C interface=42,46,47, tqeersaatrealitgarklwglrgyaevgtpeiateagvtRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_D interface=42,46,47, tqeersaatrealitgarklwglrgyaevgtpeiateagvtRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln
interface signature	QPTRYH/QTRYH/RYH/RYH

Estimated binding specificities ?

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# IC=11.262 IC/col=0.804 n_of_columns=14

specificity:

A |   0   3  24  12   0  96   0  12  24   3   0   6   9   0
C |  96  80  24   9  96   0   0  14  24   4   0  71  14   0
G |   0   9  24  66   0   0  96   9  24   3  96  10  12  96
T |   0   4  24   9   0   0   0  61  24  86   0   9  61   0

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updated Tue Sep 10 11:24:05 2024