6c31_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TETR FAMILY PROTEIN RV0078 IN COMPLEX WITH DNA
reference	Hsu et al. MBio 9 ? 2018
source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Homeodomain-like;Tetracyclin repressor-like, C-terminal domain;
reference complex	6c31_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6c31_A interface=3,33,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtPeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_B interface=3,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtpeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_C interface=42,46,47, tqeersaatrealitgarklwglrgyaevgtpeiateagvtRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_D interface=42,46,47, tqeersaatrealitgarklwglrgyaevgtpeiateagvtRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln
interface signature	QPTRYH/QTRYH/RYH/RYH

Estimated binding specificities ?

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# IC=11.344 IC/col=0.810 n_of_columns=14

specificity:

A |   0  74  13   0  87  24  63   0   0   0  13  24   5   0
C |  96   9   8  96   2  24  10  96   0   0  60  24   2   0
G |   0   8  67   0   2  24   8   0   0  96  13  24  76  96
T |   0   5   8   0   5  24  15   0  96   0  10  24  13   0

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updated Wed Jul 30 15:37:46 2025