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structure nameCRYSTAL STRUCTURE OF TETR FAMILY PROTEIN RV0078 IN COMPLEX WITH DNA
(TetR family transcriptional regulator)
referenceHsu et al. MBio 9 ? 2018
sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experimentX-ray (resolution=3.00, R-factor=0.206)
structural superfamilyHomeodomain-like;Tetracyclin repressor-like, C-terminal domain;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes6c31_ABCD 6c31_EFGH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQPTRYH

Estimated binding specificities ?

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# IC=4.636 IC/col=0.662 n_of_columns=7 specificity:   
A |   0   0   6  24  13   6  17
C |   0   0  82  24  19   4   6
G |   0  96   4  24  43  82  17
T |  96   0   4  24  21   4  56
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Dendrogram of similar interfaces ?

matrix format

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updated Sat Jan 10 09:52:00 2026