interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF TETR FAMILY PROTEIN RV0078 IN COMPLEX WITH DNA
(TetR family transcriptional regulator)
referenceHsu et al. MBio 9 ? 2018
sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experimentX-ray (resolution=3.00, R-factor=0.206)
structural superfamilyHomeodomain-like;Tetracyclin repressor-like, C-terminal domain;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes6c31_ABCD 6c31_EFGH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQPTRYH

Estimated binding specificities ?

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# IC=4.803 IC/col=0.686 n_of_columns=7 specificity:   
A |   0   0   4  24  20   4  13
C |   0   0  82  24  13   4   4
G |   0  96   4  24  45  84  18
T |  96   0   6  24  18   4  61
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Dendrogram of similar interfaces ?

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updated Fri Sep 13 21:24:07 2024