6cq2_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TOPOISOMERASE I IN COMPLEX WITH OLIGONUCLEOTIDE MTS2-12 AND MAGNESIUM (DNA topoisomerase 1)
reference	Thirunavukkaraus et al. 'Nucleic 46 7296 2018
source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experiment	X-ray (resolution=3.00, R-factor=0.192)
structural superfamily	Prokaryotic type I DNA topoisomerase;
sequence family	DNA topoisomerase; Toprim domain;
reference complex	6cqi_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6cq2_A interface=33,36,39,40,74,152,153,157,161,164,165,168,173,174,329,519,520, sgrrlvivesptkarklasylgsgyivessrgHirDlpRAasdvpakyksqpwarlgvnvdadfeplyiispeKrstvselrgllkdvdelylatdgdregeaiawhlletlkpripvkrmvfheitepairaaaehprdldidlvdaqetRRildRlygYevSPvlWkkvaPKlsagrvqsvatriivarerdrmafrsaaywdilakldasvsdpdaapptfsarltavagrrvatgrdfdslgtlrkgdevivldegsatalaagldgtqltvasaeekpyarrpyppfmtstlqqeasrklrfsaertmsiaqrlyengyitymRtdsttlsesainaartqarqlygdeyvapaprqytrkvknaqeheairpagetfatpdavrreldgpniddfrlyeliwqrtvasqmadargmtlslritgmsghqevvfsatgrtltfpgflkayvetvdelvggeaddaerrlphltpgqrldiveltpdghatnpparyteaslvkaleelgigrpSTyssiiktiqdrgyvhkkgsalvpswvafavtglleqhfgrlvdydftaamedeldeiaagnerrtnwlnnfyfggdhgvpdsvarsgglkklvginlegidarevnsiklfddthgrpiyvrvgkngpylerlvagdtgeptpqranlsdsitpdeltlqvaeelfat
interface signature	HDRAKRRRYSPWPKRST

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# IC=8.472 IC/col=1.059 n_of_columns=8

A |   0   0   0   0   0  16   0  13
C |   0   0  96  96   0  54   0  13
G |   0   0   0   0  96  13   0  13
T |  96  96   0   0   0  13  96  57

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updated Thu Sep 12 22:59:27 2024