6d6v_A : 3D-footprint complex

structure name	CRYOEM STRUCTURE OF TETRAHYMENA TELOMERASE WITH TELOMERIC DNA AT 4.8 ANGSTROM RESOLUTION (TELOMERASE REVERSE TRANSCRIPTASE)
source	TETRAHYMENA THERMOPHILA
experiment	NMR
multimeric complexes	6d6v_AD 7lma_AD 7lmb_AD 7uy6_AD 8gap_AD
redundant complexes	7lma_A 7lmb_A 8gap_A 7uy6
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6d6v_A interface=184,185,327,395,443,453,488,521,645,776,796,797, qmltrkedlltvlkqisalkyvsnlyefllatekivqtseldtqfqefltttiiaseqnlvenykqkynqpnfsqltikqviddsiillgnkqnyvqqigtttigfyveyeninlsrqtlyssnfrnllnifgeedfkyflidflvftkveqngylqvagvclnqyfsvqkqenqyiypeiqrSQifycnhmgrepgvfkssffnyqsknfscqeerdlfleftekivqnfhninfnyllkkfcklpenyqslksqvkqivqsenkanqqscenlfnslydteisykqitnflrqiiqncvpnqllgkknfkvfleklyefvqmkrFenqkvldyicfmdvfdvewfvdlknqkftqkrkyisdkrkilgdlivfiinkivipvlrynfyitekHkegsqifyyrkpiwklvskltivkleefqkypqgklriipkkgsfrpImtflrkdkqKniklnlnqilmdsqlvfrnlkdmlgqkigysvfdNkqisekfaqfiekwknkgrpqlyyvtldikkcYdsidqmkllnffnqsdliqdtyfinkyllfqrnkrpllqiqnfpyyfnlkerqiayslyddddqilqkgfkeiqsddrpfivinqdkprcitkdiihnhlkhisqynvisfnkvkfrqkrgipQglnisgvlcsfyfgkleeeytqflknaeqvngsinllmrltddylfisdsqqnalnlivqlqncannngfmfndqkittnfqfpqedynlehfkisvqnecqwigksidmntleiksiqkqtqqeinqtiNvaisiknlksqlknklrslFLnqlidyfnpninsfeglcrqlyhhskatvmkfypfmtklfqidlkkskqysvqygkentnenflkdilyytvedvckilcylqfedeinsnikeifknlyswimwdiivsylkkkkqfkgylnkllqkirksrffylkegckslqlilsqqkyqlnkkeleaiefidlnnliqdiktlipkis
interface signature	SQFHIKNYQNFL

Estimated binding specificities ?

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# IC=9.337 IC/col=0.718 n_of_columns=13

specificity:

A |   0  24  11   9  24   0   0   0  11   0  24  24   0
C |   0  24   9   9  24   0   0   0   9   0  24  24   0
G |  96  24   9  69  24  96  96   0   9  96  24  24  96
T |   0  24  67   9  24   0   0  96  67   0  24  24   0

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Dendrogram of similar interfaces ?

matrix format

  
  SGQGFGHGIGKT--NGYGQG------NG--FTLT   L                 +---------------6d6v_A    
                                             +-----------1 
  ----------------------------PGCGNG         !           +---------------6uso_A    
                                           +-3 
  ------------FC--------YA----------       ! !     +---------------------6ar1_A    
                                         --4 +-----2 
  ------------------FC--YTLC--------       !       +---------------------4ol8_E    
                                           ! 
  --------------------PGYT----------       +----------------------------4hkq_A

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updated Fri Sep 13 21:30:08 2024