interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE RBPJ-SHARP-DNA REPRESSOR COMPLEX
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceVanderWielen et al. 'Cell 26 845 2019
sourceMUS MUSCULUS
experimentX-ray (resolution=2.78, R-factor=0.197)
structural superfamilyDNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKR

Estimated binding specificities ?

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# IC=2.741 IC/col=0.392 n_of_columns=7 specificity:   
A |  12   0  10  23  22  72  38
C |  12   0   8  21  22   8  19
G |  60   0  70  31  27   8  19
T |  12  96   8  21  25   8  20
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updated Tue Dec 17 03:45:50 2024