interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE RBPJ-SHARP-DNA REPRESSOR COMPLEX
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceVanderWielen et al. 'Cell 26 845 2019
sourceMUS MUSCULUS
experimentX-ray (resolution=2.78, R-factor=0.197)
structural superfamilyDNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKR

Estimated binding specificities ?

contactlogo
# IC=2.713 IC/col=0.388 n_of_columns=7 specificity:   
A |  19  10  22  21   8  96  12
C |  19   8  27  33  70   0  60
G |  19   8  22  21  10   0  12
T |  39  70  25  21   8   0  12
scan!

home
updated Sat Aug 2 10:47:22 2025