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structure nameCRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH DNA
(Double homeobox protein 4)
referenceBosnakovski et al. 'Cell 25 2955 2018
sourceHomo sapiens
experimentX-ray (resolution=2.12, R-factor=0.201)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes5z2t_CD 6dfy_CD
reference complex6a8r_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

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# IC=13.966 IC/col=1.074 n_of_columns=13 specificity:   
A |   0   0   0  96   0  24  96  16  96   0   0  96   0
C |  16   0   0   0   0  24   0  16   0   0   0   0  96
G |  16   0  96   0   0  24   0  48   0   0   0   0   0
T |  64  96   0   0  96  24   0  16   0  96  96   0   0
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updated Sun Jun 28 15:31:05 2026