6e8c_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH DNA (Double homeobox protein 4)
reference	Bosnakovski et al. 'Cell 25 2955 2018
source	Homo sapiens
experiment	X-ray (resolution=2.12, R-factor=0.201)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6e8c_A interface=5,8,49,52,53,56,79,82,124,127,128,132, rgrgRrrRlvwtpsqsealrafernpypgiatrerlaqaigipeprvqIwfQNerSrqlrqhrresrpwpgrrgppegRrkRtavtgsqtalllrafekdrfpgiaareelaretglpesriqIwfQNrraRhp
interface signature	RRIQNSRRIQNR

Estimated binding specificities ?

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# IC=13.966 IC/col=1.074 n_of_columns=13

specificity:

A |   0   0   0  96   0  24  96  16  96   0   0  96   0
C |  16   0   0   0   0  24   0  16   0   0   0   0  96
G |  16   0  96   0   0  24   0  48   0   0   0   0   0
T |  64  96   0   0  96  24   0  16   0  96  96   0   0

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updated Tue Dec 17 03:51:57 2024