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legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH DNA
(Double homeobox protein 4)
referenceBosnakovski et al. 'Cell 25 2955 2018
sourceHomo sapiens
experimentX-ray (resolution=2.12, R-factor=0.201)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

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# IC=11.426 IC/col=0.879 n_of_columns=13 specificity:   
A |   6   6  96  96   0  24   6  24  83   0   0  96  76
C |   6   6   0   0   0  24   6  24   6   0  96   0   6
G |  78   8   0   0   0  24   8  24   6   0   0   0   6
T |   6  76   0   0  96  24  76  24   1  96   0   0   8
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updated Sat Aug 2 10:53:27 2025