6f41_ABEPUVW : 3D-footprint complex

structure name	RNA POLYMERASE III INITIALLY TRANSCRIBING COMPLEX
reference	Vorlaender et al. Nature 553 295 2018
experiment	X-ray (resolution=4.30, R-factor=?)
structural superfamily	TATA-box binding protein-like;"Winged helix" DNA-binding domain;NTF2-like;Homeodomain-like;Cyclin-like;Zinc beta-ribbon;
reference complex	5oqj_O 6cnb_O 6cnb_P 6eu0_V 6eu0_Z
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6f41_A interface=458,859,860, kevvvsetpkrikglefsalsaadivaqsevevstrdlfdlekdrapkangaldpkmgvsssslecatchgnlaschghfghlklalpvfhigyfkatiqilqgickncsaillsetdkrqflhelrrpgvdnlrrmgilkkildqckkqrrclhcgalngvvkkaaalkiihdtfrwvgkksapekdiwvgewkevlahnpeleryvkrcmddlnplktlnlfkqiksadcellgidatvpsgrpetyiwrylpappvcirpsvmmqdspasneddltvklteivwtsslikagldkgisinnmmehwdylqltvamyinsdsvnpkpirgfcqrlkgkqgrfrgnlsgkrvdfsgrtvispdpnlsidevavpdrvakvltypekvtrynrhklqelivngpnvhpganyllkrnedarrnlrygdrmklaknlqigdvverhledgdvvlfnrqPslhrlsilshyakirpwrtfrlnecvctpynadfdgdemnlhvpqteearaeainlmgvknnlltpksgepiiaatqdfitgsylishkdsfydratltqllsmmsdgiehfdipppaimkpyylwtgkqvfsllikpnhnspvvinldaknkvfvppkskslpnemsqndgfviirgsqilsgvmdksvlgdgkkhsvfytilrdygpqeaanamnrmaklcarflgnrgfsigindvtpaddlkqkkeelveiayhkcdelitlfnkgeletqpgcneeqtleakiggllskvreevgdvcineldnwnaplimatcgskgstlnvsqmvavvgqqiisgnrvpdgfqdrslphfpknsktpqskgfvrnsffsglsppeflfhaisgreglvdtavkTAetgymsrrlmksledlscqydntvrtsangivqftyggdgldplemegnaqpvnfnrswdhaynitfnnqdkgllpyaimetaneilgpleerlvrydnsgclvkredlnkaeyvdqydaerdfyhslreyingkatalanlrksrgmlglleppakelqgidpdetvpdnvktsvsqlyriseksvrkfleialfkyrkarlepgtaigaigaqsigepmnvtlgvprikeiinaskvistpiinavlvndnderaarvvkgrvektllsdvafyvqdvykdnlsfiqvridlgtidklqleltiediavaitrasklkiqasdvniigkdriainvfpendvfyrmqqlrralpdvvvkglpdisravinirddgkrellvegyglrdvmctdgvigsrtttnhvlevfsvlgieaarysiireinytmsnhgmsvdprhiqllgdvmtykgevlgitrfglskmrdsvlqlasfekttdhlfdaafymkkdavegvseciilgqtmsigtgsfkvvkgtnisekdlvpkrclfes > 6f41_B interface=278,446, deintaqdkwhllpaflkvkglvkqhldsfnyfvdtdlkkiikanqlilsdvdpefylkyvdirvgkksssstkdyltpphecrlrdmtysapiyvdieytrgrniimhkdveigrmpimlrsnkcilydadeskmaklnecpldpggyfivngtekvilvqeqlsknriiveadekkgivqasvtsstherksktyvitkngkiylkhnsiaeeipiaivlkacgilsdleimqlvcgndssyqdifavnleesskldiytqqqaleyigakvktmRrqkltilqegieaiattviahltvealdfrekalyiammtrrvvmamynpkmiddrdyvgnkrlelagqlisllfedlfkkfnndfklsidkvlkkpnrameydallsinvhsnnitsglnraistgnwslkrfkmeragvthvlsrlsyisalgmmtrissqfeksRkvsgpralqpsqfgmlctadtpegeacglvknlalmthittddeeepikklcyvlgveditlidsaslhlnygvylngtligsirfptkfvtqfrhlrrtgkvsefisiysnshqmavhiatdggricrpliivsdgqsrvkdihlrklldgeldfddflklglveyldvneendsyialyekdivpsmthleiepftilgavaglipyphhnqsprntyqcamgkqaigaiaynqfkridtllylmtypqqpmvktktielidydklpagqnatvavmsysgydiedalvlnkssidrgfgrcetrrktttvlkryanhtqdiiggmrvdengdpiwqhqslgpdglgevgmkvqsgqiyinksvptnsadapnpnnvnvqtqyreapviyrgpepshidqvmmsvsdndqalikvllrqnrrpelgdkfssrhgqkgvcgiivkqedmpfndqgivpdiimnphgfpsrmtvgkmielisgkagvlngtleygtcfggskledmskilvdqgfnysgkdmlysgitgeclqayiffgpiyyqklkhmvldkmharargpravltrqptegrsrdgglrlgemerdcviaygasqlllerlmissdafevdvcdkcglmgysgwcttcksaeniikmtipyaakllfqellsmniaprlrledifqq > 6f41_E interface= dqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfqanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsamklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqradpvalylglkrgevvkiirksetsgryasyricm > 6f41_P interface=96, lsdnaktlhsqmmskgigalftqqelqkqmgigsltdlmsivqelldknliklvkqndelkfqgvleseaqkkatmsaeealvysyieasgregiWsktikartnlhqhvvlkclkslesqryvksvksvkfptrkiymlyslqpsveldiefinslltivwrfisentqeilefitaaqvanveltpsnirslcevlvyddklekvthdcyrvtlesilqmifnyfkmfpaskhdkevvyfdewt > 6f41_U interface=9,11,39,56,64,99,101,130,131,147,153,155, sgivptlqNiVatvtlgcrldlktvalharnaeynpkrFaavimrirepkttaliFasgkmvvTgakseddsklasrkyariiqkigfaakftdfkiqNiVgscdvkfpirleglafshgtfssyepelFPgliyrmvkpkivlliFvsgkiVlTgakqreeiyqafeaiypvlsefrkm > 6f41_V interface=42,85, pvcknchgteferdlsnanndlvckacgvvsednpivseleSreatlnnarrklravsyalhipeyitdaafqwyklalannfvQgrrsqnviasclyvacrkekthhmlidfssrlqvsvysigatflkmvkklhitelpladpslfiqhfaekldladkkikvvkdavklaqrmskdwmfegrrpagiagacillacrmnnlrrthteivavshvaeetlqqrlnefkntkaaklsvqkfrendvedgearppsfvknrkkecprnlhllpttdtylskvsddpdnledvddeelnahllneeasklkeriwiglnadflleqeskrlkqeadia > 6f41_W interface=97, ckpnfpigqisenfekskmakkaklekrrhlrelrmrarqtaiqlklnpdgtmaideetmvvdrhknasieneykekvdenpfanlynygsygrgsYtdpwtveemikfykalsmwgtdfnlisqlypyrsrkqvkakfvneekkrpilielalrsklppnfdeycceikknigtvadfneklielqnehkhhmkeieeakntakeedqtaqrlndan
interface signature	PTA/RR//W/NVFFTNVFPFVT/SQ/Y

Estimated binding specificities ?

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# IC=11.300 IC/col=0.377 n_of_columns=30

specificity:

A |   0   0   0  14   0  24  24  24  24  24  24  24  24  24  24  24  24  24  96  24   6   0  24   0  78  24  24  24  24  15
C |  96   0   0  64  96  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24   6   0  24   0   6  24  24  24  24  57
G |   0   0   0  12   0  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24   8   0  24   0   6  24  24  24  24  12
T |   0  96  96   6   0  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24  76  96  24  96   6  24  24  24  24  12

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updated Sat Dec 16 10:14:44 2023