6f44_BMOUVW : 3D-footprint complex

structure name	RNA POLYMERASE III CLOSED COMPLEX CC2.
reference	Vorlaender et al. Nature 553 295 2018
experiment	X-ray (resolution=4.20, R-factor=?)
structural superfamily	TATA-box binding protein-like;"Winged helix" DNA-binding domain;Homeodomain-like;Cyclin-like;Zinc beta-ribbon;
reference complex	5oqj_O 6cnb_O 6eu0_V 6eu0_Z 6f44_M
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6f44_B interface= deintaqdkwhllpaflkvkglvkqhldsfnyfvdtdlkkiikanqlilsdvdpefylkyvdirvgkksssstkdyltpphecrlrdmtysapiyvdieytrgrniimhkdveigrmpimlrsnkcilydadeskmaklnecpldpggyfivngtekvilvqeqlsknriiveadekkgivqasvtsstherksktyvitkngkiylkhnsiaeeipiaivlkacgilsdleimqlvcgndssyqdifavnleesskldiytqqqaleyigakvktmrrqkltilqegieaiattviahltvealdfrekalyiammtrrvvmamynpkmiddrdyvgnkrlelagqlisllfedlfkkfnndfklsidkvlkkpnrameydallsinvhsnnitsglnraistgnwslkrfkmeragvthvlsrlsyisalgmmtrissqfeksrkvsgpralqpsqfgmlctadtpegeacglvknlalmthittddeeepikklcyvlgveditlidsaslhlnygvylngtligsirfptkfvtqfrhlrrtgkvsefisiysnshqmavhiatdggricrpliivsdgqsrvkdihlrklldgeldfddflklglveyldvneendsyialyekdivpsmthleiepftilgavaglipyphhnqsprntyqcamgkqaigaiaynqfkridtllylmtypqqpmvktktielidydklpagqnatvavmsysgydiedalvlnkssidrgfgrcetrrktttvlkryanhtqdiiggmrvdengdpiwqhqslgpdglgevgmkvqsgqiyinksvptnsadapnpnnvnvqtqyreapviyrgpepshidqvmmsvsdndqalikvllrqnrrpelgdkfssrhgqkgvcgiivkqedmpfndqgivpdiimnphgfpsrmtvgkmielisgkagvlngtleygtcfggskledmskilvdqgfnysgkdmlysgitgeclqayiffgpiyyqklkhmvldkmharargpravltrqptegrsrdgglrlgemerdcviaygasqlllerlmissdafevdvcdkcglmgysgwcttcksaeniikmtipyaakllfqellsmniaprlrledifqq > 6f44_M interface= ieefplkisgeeeslhvfqyanrprlvgrkpaehpfisaarykpkshlweidipldeqafynkdkaesewngvnvqtlkgvgvenngqyaafvkdmqvylvpiervaqlkpffkyiddanvtrkqedarrppnprltgsllahkvadeeanieltwaegtfeqfkdtivke > 6f44_O interface= sleqrtlnpdlflykelvkahlgeraasvigmlvalgrlsvrelvekidgmdvdsvkttlvsltqlrcvkylqetaisgkkttyyyyneegihillysgliideiitqmrvndeeehkqlvaeivqnvislgsltvedylssvtsdsmkytisslfvqlcemgyliqisklhytpiedlwqflyekhykniprnsplsdlkkrsqakmnaktdfakiinkpnelsqiltvdpktslrivkptvsltinldrfmkgrrskqlinlaktrvgsvtaqvykialrlteqkspkirdpltqtgllqdleeaksfqdeaelveektpgltfnaidlarhlpsaslinshlkilassnfpflnetkpgvyyvpysklmpvlkssvyeyviastlgpsamrlsrcirdnklvsekiinstalmkekdirstlaslirynsveiqevprtadrsasravflfrckethsynfmrqnlewnmanllfkkeklkqenstllkkanrddllpselnqlkmvnerelnvfarlsrllslwevfqma > 6f44_U interface=9,11,39,56,64,99,101,130,131,147,153,155, sgivptlqNiVatvtlgcrldlktvalharnaeynpkrFaavimrirepkttaliFasgkmvvTgakseddsklasrkyariiqkigfaakftdfkiqNiVgscdvkfpirleglafshgtfssyepelFPgliyrmvkpkivlliFvsgkiVlTgakqreeiyqafeaiypvlsefrkm > 6f44_V interface=85,220, pvcknchgteferdlsnanndlvckacgvvsednpivselesreatlnnarrklravsyalhipeyitdaafqwyklalannfvQgrrsqnviasclyvacrkekthhmlidfssrlqvsvysigatflkmvkklhitelpladpslfiqhfaekldladkkikvvkdavklaqrmskdwmfegrrpagiagacillacrmnnlrrthteivavshvaeEtlqqrlnefkntkaaklsvqkfrendvedgearppsfvknrkkecprnlhllpttdtylskvsddpdnledvddeelnahllneeasklkeriwiglnadflleqeskrlkqeadia > 6f44_W interface=28,72, ckpnfpigqisenfekskmakkaklekRrhlrelrmrarqknasieneykekvdenpfanlynygsygrgsYtdpwtveemikfykalsmwgtdfnlisqlypyrsrkqvkakfvneekkrpilielalrsklppnfdeycceikknigtvadfneklielqnehkhhmkei
interface signature	///NVFFTNVFPFVT/QE/RY

Estimated binding specificities ?

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# IC=7.099 IC/col=0.887 n_of_columns=8

specificity:

A |  13  96  13  96  96  96  24  96
C |  16   0  16   0   0   0  24   0
G |  13   0  13   0   0   0  24   0
T |  54   0  54   0   0   0  24   0

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updated Wed Jul 30 17:30:45 2025