6f59_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN BRACHYURY (T) G177D VARIANT IN COMPLEX WITH DNA
reference	Burgess-Brown et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=2.15, R-factor=?)
structural superfamily	p53-like transcription factors;
reference complex	6f59_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6f59_A interface=29,150,151,167,171, elrvgleeselwlrfkeltnemivtkngRrmfpvlkvnvsgldpnamysflldfvaadnhrwkyvngewvpqapscvyihpdspnfgahwmkapvsfskvkltnklngggqimlnslhkyeprihivrvgdpqrmitshcfpetqfiavTAyqneeitalkikynpFakaFldakers > 6f59_B interface=30,157,158,174,177,178, gelrvgleeselwlrfkeltnemivtkngRrmfpvlkvnvsgldpnamysflldfvaadnhrwkyvngewvpggkpepqapscvyihpdspnfgahwmkapvsfskvkltnklngggqimlnslhkyeprihivrvgdpqrmitshcfpetqfiavTAyqneeitalkikynpFakAFldakers
interface signature	RTAFF/RTAFAF

Estimated binding specificities ?

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# IC=6.260 IC/col=0.348 n_of_columns=18

specificity:

A |  13  24  24  24   0  82  24  24  24  24  24  20   0   0  24  24  24  89
C |  22  24  24  24  96   2  24  24  24  24  24  13   0   0  24  24  24   1
G |  13  24  24  24   0   6  24  24  24  24  24  54   0  96  24  24  24   0
T |  48  24  24  24   0   6  24  24  24  24  24   9  96   0  24  24  24   6

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updated Wed Jul 30 17:33:14 2025