6fbr_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN MEP DR1 RESPONSE ELEMENT, PH 4.2
reference	Poussin-Courmontagne et al. 'Mol. 481 44 2019
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fbr_A interface=23,26,30,31, tkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqee > 6fbr_B interface=4,28,31,35,36,80, gshMftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrclidkrqrnrcqycryqkclamgmkreavqeeRq
interface signature	EKKR/MEKKRR

Estimated binding specificities ?

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# IC=10.197 IC/col=0.850 n_of_columns=12

specificity:

A |   7   0  73  96   0  24  24   7   0  75   0   0
C |  14   0   7   0  96  24  24   7   0   7  96  96
G |   7  96   7   0   0  24  24   9  96   7   0   0
T |  68   0   9   0   0  24  24  73   0   7   0   0

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updated Tue Jan 6 03:42:16 2026